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News | 2014.12.11
Malaria: formal identification of the artemisinin resistance gene
Together with teams from Columbia University (USA), CNRS in Toulouse and NIH/NIAID (USA), Institut Pasteur scientists based in Paris and Cambodia have recently provided the key demonstration that K13 is indeed the main determinant of artemisinin resistance in Plasmodium falciparum parasites. This work is a landmark for the scientific community, as it provides a validated molecular marker for...
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News | 2020.06.16
Novel neurotropic arbovirus identified in France: the Umbre virus
The Institut Pasteur's Pathogen Discovery Laboratory and the neuropathology laboratory at Pitié-Salpêtrière Hospital set out to identify pathogens in fatal cases of encephalitis of unknown etiology. In two immunosuppressed patients, the Umbre virus (genus Orthobunyavirus) was identified. This virus infects neurons in the cerebral cortex, the spinal cord and the liver. The discovery of a novel...
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Document de presse | 2014.12.11
Malaria: formal identification of the artemisinin resistance gene
Together with teams from Columbia University (USA), CNRS in Toulouse and NIH/NIAID (USA), Institut Pasteur scientists based in Paris and Cambodia have recently provided the key demonstration that K13 is indeed the main determinant of artemisinin resistance in Plasmodium falciparum parasites. This work is a landmark for the scientific community, as it provides a validated molecular marker for...
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Document de presse | 2013.12.12
A prime target for the development of anti-inflammatories
For the first time, scientists from the Institut Pasteur and Inserm have demonstrated the key role played by a particular molecule in intestinal infection. The study was published online in Immunity on December 12, 2013. The molecule, known as ATP, serves as a trigger signal for the inflammatory response targeting pathogenic agents. Using the Shigella flexneri model, the scientists have also...
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Document de presse | 2014.10.13
Human papillomavirus linked to auto-immune disease
Erosive oral lichen planus (OLP) is an auto-immune disease affecting skin and mucous membranes which results in an abnormal immune response against mucocutaneous cells. Today, scientists at the Institut Pasteur, Inserm, Paul Sabatier University (Toulouse) and the CNRS have proven that the immune cells involved in OLP are the same as those activated during an immune response to human...
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Document de presse | 2023.03.07
A New Milestone in the Development of an Effective Allergic Asthma Vaccine
To combat allergic asthma, which affects millions of people worldwide, scientists from Inserm, CNRS and Université Toulouse III-Paul Sabatier at the Infinity laboratory[1], Institut Pasteur and French company NEOVACS are developing and testing a new vaccine. In their previous study, the teams had shown it to be effective in producing antibodies capable of neutralizing human immune proteins that...
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Document de presse | 2013.12.18
Molecular marker discovered for detecting artemisinin-resistant forms of malaria
Scientists at the Institut Pasteur in Paris, the Institut Pasteur in Cambodia, the French National Center for Scientific Research (CNRS), and the U.S. National Institutes of Health (NIAID/NIH) have identified a molecular marker for detecting malaria parasites with resistance to artemisinin derivatives (major components in antimalarial medicine or drug treatments currently recommended by the World...
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Document de presse | 2020.10.08
AIDS: Furthering Knowledge of Natural HIV Infection Control Mechanisms
A further step has just been taken in understanding the mechanisms that allow some individuals to control HIV infection without treatment.A research team led by Dr. Asier Sáez-Cirión (Institut Pasteur) and Dr. Bruno Vaslin (IDMIT[1], CEA-Inserm-Université Paris Saclay) observed for the first time that the antiviral activity of CD8+ T cells of "controller" macaques infected with the simian...
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News | 2021.02.02
Glioblastoma : Tunelling nanotubles could be a new therapeutic target
Cancer is the leading cause of mortality in France. In the last 40 years, survival rates have increased for several types of cancer, such as breast or prostate cancer. However, brain cancer is still an incurable disease, as it usually becomes resistant to therapy and relapses in a relatively short time. The outcome is almost inexorably the patient death. Researchers headed by Chiara Zurzolo at...
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Document de presse | 2016.01.27
Tuberculosis: discovery of a critical stage in the evolution of the bacillus towards pathogenicity
It is the disappearance of a glycolipid from the bacterial cell envelope during evolution that may have considerably increased the virulence of tuberculosis bacilli in humans. Scientists from the CNRS, the Institut Pasteur and the Université Toulouse III – Paul Sabatier[1] have shown that this disappearance modified the surface properties of Mycobacterium tuberculosis, favoring its...