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  1. Document de presse | 2006.04.26

    A breakthrough in the fight against multiresistance to antibiotics

    Multiresistance to antibiotics is a major public health problem. In hospitals, multiresistant pathogens are the main obstacle hindering the control of nosocomial infections. One of the main ways of spreading such resistance is the transfer between bacteria of a class of particularly mobile elements, called integrons, which are carriers of these resistance factors. In a study published today ? in...

  2. Document de presse | 2005.09.05

    Cholera: How Parasites Make Bacteria Pathogenic

    Vibrio cholerae, the bacteria that causes cholera, is made pathogenic by one of its parasites, the CTX virus. This virus enables the vibrio to produce a toxin that causes the lethal diarrhea of cholera. Researchers at the CNRS and Institut Pasteur have recently proven, in a work published in Molecular Cell, which adaptive method the CTX bacteriophage uses to propagate itself so effectively in the...

  3. CNR/CCOMS | 2019.11.19

    Emerging animal pathogens in humans

    World Organization for Animal Health - Collaborating Center (WOAHCC) for the "detection and identification in humans of emerging animal pathogens and development of tools for their diagnoses".The Environment and Infectious Risks Unit, Laboratory for Urgent Response to Biological Threats, and Pathogen Discovery Laboratory host this WOAHCC.HeadsJean-Claude ManuguerraMarc EloitDetection and...

  4. Document de presse | 2009.07.19

    How pathogens have shaped genes involved in our immune system

    A recent study on human genetics on various populations across the world conducted by researchers from the Institut Pasteur and the CNRS has shown how pathogens can shape the patterns of genetic diversity of our immune system over time. Results show that bacteria, fungi and parasites, unlike viruses, appear to have allowed the introduction of mutations in the genes of some proteins of the innate...

  5. News | 2020.11.26

    Presbycusis: ultra-rare genetic mutations responsible for a quarter of cases occurring around the age of 50

    Presbycusis, or age-related hearing loss, involves genetic and environmental factors. A genomic analysis can identify gene variants whose pathogenicity subsequently needs to be confirmed. As a general rule, frequent variants have little or very little effect; it is their cumulative impact in several genes that explains the impairment. Ultra-rare variants, on the other hand, have a strong impact...

  6. Document de presse | 2024.10.15

    Resistance mutations to nirsevimab are rare in respiratory syncytial virus (RSV)

    Nirsevimab is an antibody targeting the respiratory syncytial virus (RSV). Available in France since September 2023, it is indicated in neonates and infants for the prevention of bronchiolitis caused by RSV. However, its widespread use raises the question of the emergence of resistance mutations. The POLYRES study, the largest prospective surveillance study of nirsevimab breakthrough infections...

  7. News | 2022.11.10

    ERC grants: new funding awarded in October 2022

    Since they were launched in 2007, European Research Council (ERC) grants have become a mark of scientific excellence. Three new ERC Synergy Grants have recently been awarded for international projects involving scientists working on the Institut Pasteur campus.

  8. Portrait | 2023.06.12

    Camille Berthelot, the Indiana Jones of endometriosis

    Painful periods, menstruation, endometriosis, diagnostic odyssey – Camille Berthelot is not afraid to delve into topics that are sometimes seen as taboo but affect a large part of the world's population. She specializes in comparative genomics of species and leads her own group at the Institut Pasteur. She and her team are currently working to find a biological marker that could be used for early...

  9. News | 2020.05.14

    LuLISA project, bioluminescence as a tool for human diagnostics, from allergy to Covid19

    The LuLISA (Luciferase-Linked ImmunoSorbent Assay) research project aims developing high throughput serological tests for epidemiological studies at local, regional or nation scales. In a recent scientific publication, concerning the detection and dosing of IgE specific to several allergens in patients’ blood samples, the use of LuLISA proves to be a vastly improved detection method in...

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