DURABLE: a large-scale project on Emerging diseases within the EU4Health European program

Kick-off meeting of the DURABLE project, held in Paris from 28 February to 1 March 2023. Copyright: Institut Pasteur

The European project DURABLE (Delivering a Unified Research Alliance of Biomedical and public health Laboratories against Epidemics) is a unique consortium of research and public hessalth laboratories across Europe which will help to build stronger, more resilient and more accessible health systems. DURABLE is coordinated by Dr. Jean-Claude Manuguerra (Institut Pasteur) with Professor Marion Koopmans (Erasmus Medical Center, the Netherlands) and Roberto Bruzzone (HKU-Pasteur Research Pole).

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The European project DURABLE, led by the Institut Pasteur, has been launched in February, 2023.

With infectious disease epidemics on the increase, a strong network of world-class basic and translational research institutes is needed to respond to health threats. The unique DURABLE consortium of European research and public health laboratories has been funded under the EU4Health European program with €25 million from the European Union over four years (2023-2027). In addition to developping a one-stop shop, this project will establish a sustainable network of laboratories and research institutes that can address the barriers of better preparedness, and provide alerts, real-time scientific data and integrated analyses to European authorities, such as HERA and ECDC.

The Pasteur Network is a DURABLE project partner.

Read more about the launch of the project - Emerging diseases: DURABLE, a European project led by the Institut Pasteur

About the DURABLE project

Outbreaks of infectious diseases are increasing due to multiple local and global interaction changes disrupting the fragile balance of the complex human-animal-environment ecosystem. The increased frequency and complexity of health threats require a different, unified form of preparedness and a coordinated, fast, reliable and effective emergency response.

DURABLE is a tailored solution to this recognised need - a strong network of world-class basic and translational research institutes and public health centres across Europe with an outstanding track record in public health support with global reach. DURABLE aims to provide high-quality scientific information in record time to support HERA’s decision-making in preparing for and responding to cross-border health threats and assessing the impact of countermeasures.

DURABLE will coordinate a global collaboration, from pathogen detection, evolutionary analysis and threat characterisation, with One Health approach, to data and information collection and sharing, for optimal threat response. DURABLE is a unique multidisciplinary consortium with complementary expertise to meet this challenge and build productive interactions with HERA and other stakeholders.

Due to their outstanding track record and experience in the field, the DURABLE consortium is competent from day one. DURABLE will develop and validate a roadmap for rapid deployment of key countermeasures, test the robustness of the network, and assess key aspects of its emergency mode when simula¬ting or dealing with identified threats. Additionally, DURABLE will focus on long-term sustainability by focusing on capacity building, training the next generation of researchers and developing pandemic preparedness training modules for the network and beyonds.

DURABLE project objectives

  • DURABLE will be a one-stop shop for diagnostics, research, preparedness and response to current and future health threats for the benefit of citizens in the EU and worldwide.
  • DURABLE will establish a sustainable network of laboratories and research institutes that can address the barriers of better preparedness, and provide alerts, real-time scientific data and integrated analyses to HERA.
  • DURABLE will:

- Develop and use both non-targeted and targeted methods for identification of known and new threats
- Coordinate, integrate, analyse and share the output for rapid and direct use in public health decision making
- Develop targeted studies to guide further evidence gathering in response to alerts

 

Duration 4 years

2023-2027

10 Specific objectives

 

19 Partners & 1 Affiliated Entity

in 15 EU Countries

 

170 Experts

 

DURABLE

 

29 Deliverables

 

Budget 30M€

25M funded by HERA

 

17 Milestones

48 Tasks

Distribued in 11 WPs

At the Institut Pasteur

By facilitating contacts between the main players and stakeholders in the field, the Institut Pasteur Grant Office (GO) has played a central role in shaping the network at record speed. Key to the success of DURABLE was also the GO’s expertise in identifying and organizing goals, priorities, management procedures and in preparing the ground for a fast-acting new network of experts in support of EU citizens.

 

DURABLE partners & affiliated entities
Partenaires et entités affiliées de DURABLE

  1. Institut Pasteur (IP) France

  2. Pasteur Network (PN)

  3. Katholieke Universiteit Leuven (KU LEUVEN) Belgium

  4. Statens Serum Institut (SSI) Denmark

  5. Friedrich Loeffler Institut - Bundesforschungsinstitut fuer Tiergesundheit (FLI) Germany

  6. Charite - Universitaetsmedizin Berlin (CHARITE) Germany

  7. Erasmus Medisch Centrum Rotterdam (EMC) Netherlands

  8. Partikas Drosibas, Dzivnieku Veselibas un Vides Zinatniskais Institutsbior (BIOR) Latvia

  9. Universite d’Aix Marseille (AMU) France

  10. Rijksinstituut voor Volksgezondheid en Milieu (RIVM) Netherlands

  11. Universita Degli Studi di Padova (UNIPD) Italy

  12. Uniwersytet Jagiellonski (JU) Poland

  13. Agencia Estatal Consejo Superior de Investigaciones Cientificas (CSIC) Spain

  14. Helsingin Yliopisto (UH) Finland

  15. Aristotelio Panepistimio Thessalonikis (AUTH) Greece

  16. Instituto Nacional de Saúde Dr. Ricardo Jorge (INSA) Portugal

  17. Univerzita Karlova (CU) Czech Republic

  18. Istituto Superiore di Sanità (ISS) Italy

  19. Tartu Ulikool (UTARTU) Estonia

  20. Hrvatski Zavod za Javno Zdravstvo (CIPH) Croatia

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