human genetics
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2021.05.21
Dominant optic atrophy (DOA) is one of the most common forms of mitochondrial disease. It can be caused by genetic mutations in OPA1 resulting in mitochondrial...
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2021.05.06
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Biobanks are entities ensuring the governance, management and conservation of biological resources, living cells, viruses, bacteria and...
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2020.10.16
Hantaviruses are rodent-borne viruses causing serious zoonotic outbreaks worldwide for which no treatment is available. X-ray structures of the hantavirus...
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2020.07.09
Diagnosis of sleeping sickness, a neglected tropical disease caused by African trypanosomes, relies on the detection of parasites in blood. Following their...
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2020.02.08
In nature, female mosquitoes take successive blood meals during which they are exposed to a variety of microbes present in the host. In Africa, Trypanosoma...
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2020.08.04
Resistance to artemisinin, the main component of current antimalarial treatments recommended by WHO, is widespread in South-East Asia, but has not been...
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2020.10.17
Ludovic Deriano’s Unit studied cells mutated for NHEJ, the canonical repair pathway for DNA double-strand break. The researchers showed that those transformed...
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2021.05.03
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Emerging and re-emerging viruses are key players among the different pathogens that have caused recent epidemics, as attested by several...
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2020.03.05
Cells in vivo organize into 3D structures that underlie the shape and mechanics of tissues, as well as their biological function. Researchers mapped how...
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2020.07.16
Triplet repeat expansions are responsible for more than two dozen neurological and developmental disorders. Shortening these repeats with endonucleases could...