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Fiche maladie | 2015.10.06
Malaria
Malaria is a disease transmitted by parasites of the genus Plasmodium. According to WHO figures, the disease caused 608,000 deaths worldwide in 2022. For several years now, parasites have been developing resistance to antimalarial drugs and mosquitoes are increasingly less susceptible to insecticides.
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Fiche maladie | 2016.07.08
Staphylococci
Staphylococci are pathogenic bacteria responsible for a broad spectrum of diseases with varying degrees of severity. They are one of the main causes of nosocomial infections (hospital-acquired infections) but can also be acquired outside hospitals. They are part of the natural skin flora, specifically colonizing external mucous membranes, but they are also often found in the environment (in...
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News | 2016.11.10
Chikungunya spreads in and around homes with women at highest risk
The mosquito-borne disease chikungunya seems to spread from infections centered in and around the home, with women much more likely to become infected. This finding was revealed by a new study conducted by the Institut Pasteur in Paris, in collaboration with the US-based Johns Hopkins Bloomberg School of Public Health and the International Centre for Diarrhoeal Disease Research in Bangladesh (...
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Article | 2017.01.03
Wollman class (2016-2019)
Ph.D. StudentUndergraduate studiesLaboratoryThesis AdvisorLab HeadDoctoral SchoolPh.D. projectUsama ASHRAFHuazhong Agricultural University, Wuhan, ChinaMolecular Genetics of RNA VirusesNadia NaffakhSylvie van der WerfBioSPCStructure/function analysis of the interface between influenza virus transcriptional machinery and the cellular splicing machineryGiorgia BARUCCIAlma Mater...
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Article | 2017.03.09
Persistent Viral Infections and Immune evasion
SummaryThis course is located at the intersection between virology and immunology. The aim of the course is to educate graduates and post-graduates with understanding and expertise in virology, with a particular focus on persistent viruses and the mechanisms by which viruses escape from the immune system. This specific theoretical knowledge will provide students with the critical judgement and...
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Document de presse | 2017.07.20
Gene therapy: first results in children with Sanfilippo B syndrome
On July 13, 2017, the journal Lancet Neurology published the results of a gene therapy trial conducted in four children with Sanfilippo type B syndrome (also known as MPS IIIB). This trial is the achievement of a two-decade partnership with financial support of AFM-Téléthon and the cooperation of the charity "Vaincre les Maladies Lysosomales" (VML). After monitoring of the treated children for 30...
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Article | 2017.10.13
Afribiota project: Childhood malnutrition
Malnutrition is a leading cause of child morbidity and mortality in low-income countries. The state of malnutrition is maintained by a chronic inflammation of the intestine observed in a large proportion of children living in unsanitary conditions. This syndrome called pediatric environmental enteropathy has so far been poorly studied. The Afribiota project aims to better characterize this...
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Document de presse | 2017.12.11
How Zika virus induces congenital microcephaly
A team of researchers from ZIKAlliance discovers a specific mechanism of the infectionEpidemiological studies show that in utero fetal infection with the Zika virus (ZIKV) may lead to microcephaly, an irreversible congenital malformation of the brain characterized by an incomplete development of the cerebral cortex. However, the mechanism of Zika virus-associated microcephaly remains unclear. An...
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News | 2018.04.16
Halima Maïnassara: from field investigator to director of CERMES in Niger
In February 2017, Dr Halima Maïnassara is the first woman from Niger to be appointed Director General of the Center for Medical and Health Research (CERMES) in Niamey. Physician, epidemiologist expert in meningitis, she started to work for this public institution, member of the Institut Pasteur International Network, in February 2005 as a field investigator.Since primary school, Halima Boubacar...
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Document de presse | 2018.06.14
HIV: “controller” patient research holds promise for cell therapy
Rare patients infected by HIV spontaneously control viral replication without antiretroviral therapy, and do not go on to develop AIDS. The ability of these patients, known as "HIV controllers", to limit HIV replication appears to result from a highly effective immune response. Scientists from the Pasteur Institute and Inserm, together with colleagues from Monash University, Melbourne, found that...