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News | 2018.09.26
2016 yellow fever outbreak in Brazil: tiger mosquitoes are also capable of transmitting the virus
Since December 2016, Brazil has been grappling with its worst yellow fever outbreak for several decades. To date, there have been 2,043 human cases including 676 fatalities, mainly occurring in ten Brazilian states including Rio de Janeiro and São Paulo. These two states, the most heavily populated in Brazil, had been free of yellow fever for nearly 70 years. Research by scientists at the...
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Document de presse | 2019.07.11
High-risk pregnancy: the interferon effect
Discovery of a cellular mechanism involved in abnormal placental development during some high-risk pregnancies.High-risk pregnancies occur frequently and may be caused by various factors. It is estimated that 10 to 20% of pregnant women miscarry during their first trimester of pregnancy. Slow fetal growth may also arise as a result of maternal infection with certain microbes, parasites or viruses...
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Document de presse | 2020.05.26
COVID-19: the vast majority of patients with a minor form develop neutralizing antibodies
Teams from Strasbourg University Hospital and the Institut Pasteur carried out a study among hospital staff on the two sites of Strasbourg University Hospital. After observing 160 people with minor forms of COVID-19, the scientists concluded that nearly all the patients developed antibodies within two weeks of being infected. In 98% of the patients, neutralizing antibodies were detected after 28...
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Fiche maladie | 2015.10.06
West Nile
West Nile virus is transmitted to humans by mosquitoes. It causes sudden fever, sometimes associated with neurological complications that can be severe in many animal species. Since it was first identified in East Africa, the virus has been observed on every continent. It is currently endemic in the Mediterranean Basin, Central Europe and North America, where it is responsible for fatal human...
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News | 2021.10.15
The Institut Pasteur de Guinée: a young institute in the midst of the COVID-19 crisis
The decision to set up an Institut Pasteur in Guinea was made in 2014 in response to the Ebola crisis. It reflects the joint determination of France and Guinea to tackle emerging outbreaks on a long-term basis for the welfare of the population. When the COVID-19 pandemic struck, how was this young institute able to fulfill its remit as a front-line laboratory?When the first case of COVID-19 was...
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Document de presse | 2022.02.02
New anti-HIV antibody function discovered: tethering of viral particles at the surface of cells
Teams at the Institut Pasteur, CNRS, Vaccine Research Institute (VRI) and Université de Paris have discovered a new function of anti-HIV-1[1] antibodies by applying cutting-edge microscopy techniques to in vitro viral cultures. The scientists found that certain antibodies already known for effectively targeting HIV-1 envelope (Env) protein can prevent infected cells from releasing viral particles...
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Document de presse | 2022.03.29
SARS-CoV-2: neutralization of BA.1 and BA.2 by therapeutic monoclonal antibodies
The SARS-CoV-2 Omicron BA.1 sublineage has been supplanted in many countries by the BA.2 sublineage. Although Omicron is responsible for less severe forms in the general population, immunocompromised people are still at higher risk of developing severe forms of COVID-19. Several monoclonal antibodies are currently available in clinical practice as a preventive treatment for these patients....
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Document de presse | 2022.04.12
HIV: The Antibodies of "Post-treatment Controllers"
A very small percentage of people with HIV-1, known as "post-treatment controllers" (PTCs), are able to control their infection after interrupting all antiretroviral therapy.Understanding the fundamental mechanisms that govern their immune response is essential in order to develop HIV-1 vaccines, novel therapeutic strategies to achieve remission, or both.A recent study investigated the humoral...
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News | 2022.06.08
The role of social sciences in the response to an epidemic: the example of the COVID-19 pandemic
A lesser known but equally crucial dimension in managing and responding to an epidemic is social sciences in health, which can shed light on populations' understanding, perception and acceptance of the risks associated with diseases. The COVID-19 pandemic is no exception. As the disease spread across the planet, clear differences in perception by populations were observed in different countries,...
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News | 2022.06.14
A New Drug Target against Malaria
Malaria is a disease that continues to cause tremendous suffering and mortality in the tropics. This disease is caused by Plasmodium parasites. The species Plasmodium falciparum causes the severest and most deadly form of malaria. Scientists from Institut Pasteur studied the blood stage of the parasites and found a mechanism which could lead to new and efficient drugs against Malaria.Despite...