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News | 2016.08.10
Disturbing prevalence of antibiotic-resistant Enterobacteriaceae in Central African children
Nearly 59% of Central African children under 5 years, are asymptomatic carriers of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E); one of the highest prevalence ever described in the world. These bacteria are resistant to every antibiotics currently marketed in Central African Republic.Alain Farra, Thierry Frank and Sébastien Breurec (1), from Bacteriology Laboratory at the...
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Fiche maladie | 2015.10.06
Leishmaniasis
Leishmaniasis is a parasitic disease that causes severely debilitating cutaneous or visceral lesions, which can be fatal if left untreated. The plural form "leishmaniases" is sometimes used, as the disease is actually a group of diseases caused by different parasites of the genus Leishmania, transmitted by the bites of sandflies. These parasitic diseases are considered emerging neglected diseases...
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News | 2021.02.08
Antibiotic response in bacteria: the role of membrane vesicles
Membrane vesicles (also known as extracellular vesicles) are produced by all kinds of organisms. They are small lipid bags that come off a donor cell and get internalized by a recipient cell. Their role is to carry biological information and they are described as key intercellular communication players. However, their role in the microbial world is still very much unknown. Researchers from the...
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Document de presse | 2021.08.19
Immune checkpoint inhibitors improve cellular immunity against SARS-CoV-2
Researchers and doctors from the AP-HP, the Institut Pasteur, the University of Paris and the Sorbonne University, have carried out work on the effect of immune checkpoint inhibitors (anti-PD1 and anti-CTLA4) on cellular immunity against SARS-CoV-2. This work, the results of which suggest that these treatments are not deleterious during infection with COVID-19 and, on the contrary, seem to...
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Article | 2021.10.18
Yersin Class (2014-2017)
Ph.D. StudentUndergraduate studiesLaboratoryThesis AdvisorLab HeadDoctoral SchoolPh.D. projectEugenia COVERNTONUniversidad Nacional de Rosario, ArgentinaStructural VirologyFrançois Bontems / Giovana Barba-SpaethFélix ReyMTCIStructure-function studies on yellow fever virusAnna FUNKThe London School of Hygiene and Tropical Medicine (LSHTM), UKEpidemiologyof Emerging ...
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Document de presse | 2021.10.11
SARS-CoV-2 Alpha, Beta and Delta variants display enhanced viral fusion properties compared to ancestral strains
In a new study published in EMBO Journal on October 2, 2021, scientists from the Institut Pasteur, the CNRS, Université de Paris, the Vaccine Research Institute and Sorbonne University examined the fusion mechanisms of different SARS-CoV-2 variants: Alpha (initially identified in the United Kingdom), Beta (initially identified in South Africa) and Delta (initially identified in India). The Delta...
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News | 2023.11.15
The Institut Pasteur pays tribute to Dr. Grancher, physician and “Pasteurian”
On November 7, 2023, the Grancher Foundation celebrated its 120th anniversary on the Institut Pasteur campus. The Foundation was established by Dr. Joseph Grancher. It was an opportunity for the Institut Pasteur's President to pay tribute to the physician best known for his work on tuberculosis – a disease that the Institut Pasteur continues to fight.
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News | 2023.02.20
Two effective new antiviral drugs for SARS-CoV-2
Scientists at the Institut Pasteur have successfully synthesized two novel molecules that are active against several variants of the virus responsible for COVID-19. The discovery could inspire new families of antiviral drugs against future emerging viral diseases.
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News | 2022.09.01
Malaria: blood stage of the parasite recreated in vivo to help tackle the disease
By engrafting human hematopoietic stem cells into mice, a team from the Institut Pasteur, Inserm and the CNRS was able to maintain the Plasmodium vivax parasite in vivo, providing a novel model to explore therapeutic strategies.
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News | 2017.06.29
Viral hepatitis: the challenge of communication in Africa
WHO adopted in 2016 a global strategy to eliminate hepatitis B and C by 2030. On the basis of anthropological analyses conducted in multiple African countries, a group of researchers, including some from the Institut Pasteur, suggest that to achieve these goals it is essential to improve the communication about viral hepatitis. According to WHO, viral hepatitis caused 1.34 million deaths in...