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Document de presse | 2021.03.26
COVID-19: analysis of the sensitivity of the UK (B.1.1.7) and South African (B.1.351) variants to SARS-CoV-2 neutralizing antibodies
The B.1.1.7 and B.1.351 variants of SARS-CoV-2 were first detected in the UK and South Africa respectively, and have since spread to many other countries. Scientists from the Institut Pasteur joined forces with Orléans Regional Hospital, Tours University Hospital, Créteil Intercommunal Hospital, Strasbourg University Hospital and Georges Pompidou European Hospital to study the sensitivity of...
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News | 2020.02.05
Meningococci: an example of genomics used as an epidemiological tool
By examining vaccine coverage of invasive meningococcal infections in conjunction with genomic and pathophysiological analyses, it was possible to detect a new genotype in meningococcal serogroup W and characterize the emergence of the resulting bacterial strain. This combined approach has been a useful decision-making tool in implementing measures to control invasive meningococcal infections in...
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News | 2022.04.14
Monoclonal antibody SPK001: potent and broad neutralization activity across all SARS-CoV-2 variants of concern
SPK001, the monoclonal antibody developed by SpikImm, a biotech company founded by the Institut Pasteur and Truffle Capital, has demonstrated a potent and broad neutralization activity across all SARS-CoV-2 variants of concern, including omicron (BA.1 and BA.2). Originally developed in the Humoral Immunology lab headed by Dr Hugo Mouquet at the Institut Pasteur (joint research unit Inserm),...
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Article | 2025.01.20
Immunology
The complexity of the immune system is a never-ending source of fascination for scientists. The Department of Immunology is composed of teams that investigate the body's natural system of protection against disease.
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Document de presse | 2016.03.03
Antibodies capable of eliminating HIV-infected cells
Researchers from the Institut Pasteur, CNRS and Vaccine Research Institute (ANRS/Inserm) have recently shown that some effective antibodies recognize cells infected by the human immunodeficiency virus (HIV) and trigger their destruction by the immune system. This discovery sheds new light on the mechanism of action of these specific antibodies, which are currently undergoing clinical trials....
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News | 2020.07.06
Hepatitis B: natural controllers shed light on immunity mechanisms
Infections in humans caused by the hepatitis B virus (HBV) represent a major public health problem. Despite the availability of effective protective vaccines, more than 250 million individuals worldwide are chronically infected according to WHO estimates. HBV infection is associated with cirrhosis, liver failure and hepatocellular carcinoma, responsible for approximately a million deaths every...
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Document de presse | 2021.03.07
COVID-19: neutralizing immune response lasts longer in women than in men
As part of the SEROCoV-HUS study, teams from Strasbourg University Hospital and the Institut Pasteur monitored 308 hospital staff who had previously contracted a mild form of SARS-CoV-2. The scientists demonstrated that neutralizing antibodies could be detected in 84% of them up to 6 months after infection, but that the level fell more quickly in men than in women. These results seem to suggest...
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Document de presse | 2022.12.13
Epidemics, pandemics: a never-ending story? – a look back at the conference held on December 7, 2022
In connection with the bicentenary of Louis Pasteur’s birth, a conference entitled "Epidemics, pandemics: a never-ending story?" was held on Wednesday December 7 at the Institut Pasteur under the high patronage of the French President, Emmanuel Macron. The conference marked the end of a year of events highlighting not only the importance of research in tackling infectious diseases, but also the...
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Document de presse | 2024.08.19
Mpox outbreak: "We are ready to test and vaccinate"
On Wednesday August 14, in response to the active circulation of clade 1 monkeypox virus (MPXV) in Central Africa and the recent expansion of a subtype (1b) thought to be more lethal and transmissible in East Africa, the World Health Organization (WHO) declared a public health emergency of international concern (PHEIC), paving the way for enhanced coordination between regional health systems and...
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News | 2018.10.04
Multicentric research has identify Leptospira bacteria circulating in Uruguay
In a pioneering work, a multidisciplinary team of researchers from “Miguel C. Rubino” Lab at the Ministry of Livestock (MGAP), the National Agricultural Research Institute (INIA), the state university (Udelar) the Institut Pasteur in Montevideo and the Institut Pasteur (Paris) have identified for the first time the pathogenic strains of the Leptospira bacteria that circulate in Uruguay infecting...