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News | 2024.09.18
Whooping cough: how do we explain its resurgence in 2024 in France?
In a study coordinated by the Institut Pasteur, scientists describe the dynamics of the whooping cough epidemic in 2024 in France, the worst in 25 years. The scientists also sequenced the genome of almost 70 bacterial isolates collected during the outbreak from January to mid-2024. These analyses allowed them to put forward several theories explaining the current resurgence in circulation of the...
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Document de presse | 2022.07.13
Light shed on SARS-CoV-2 replication in bat cells
Bats are reservoir species for numerous viruses including coronaviruses. Given that they do not appear to be affected by diseases transmitted by these viruses, there is potential benefit in understanding how their immune system regulates infection. Scientists at the Institut Pasteur and the CNRS studied SARS-CoV-2 replication in bat cells, which involved using real-time imaging techniques for the...
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News | 2022.11.14
Monkeypox: a detailed profile of the disease
Physicians and scientists from the Institut Pasteur, the Pasteur Network and ANRS | Emerging Infectious Diseases have conducted a review of the medical and scientific literature about monkeypox. The review, which paints a complete picture of the disease, was published in the New England Journal of Medicine on October 26, 2022. What are the signs of this disease? Where does it come from? How is it...
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Portrait | 2022.12.13
Pierre-Marie Lledo: a neuro-optimist in work and in life
Perception, emotions, behavior, decision-making, memory, good mental health, depression – these are some of the research topics that interest Pierre-Marie Lledo. With his team of biologists, physicians, mathematicians, biophysicists and biochemists, he is working to uncover some of the most intimate mechanisms in the brain.
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Document de presse | 2023.01.13
Using paleogenomics to elucidate 10,000 years of immune system evolution
Scientists from the Institut Pasteur, Université Paris Cité, the CNRS and the Collège de France have used paleogenomics to trace 10,000 years of human immune system evolution. They analyzed the genomes of more than 2,800 individuals who lived in Europe over the past ten millennia. They were able to date the increase in frequency of most of the mutations that are advantageous in defending against...
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Document de presse | 2023.10.25
New discovery concerning receptors used by coronaviruses to enter human cells
The SARS-CoV-2 virus responsible for COVID-19 can cause severe acute respiratory syndrome, contrasting with other coronaviruses that were known to cause mild seasonal colds prior to its emergence in 2019. This raises the question of why one coronavirus affects humans more severely than another. Scientists at the Institut Pasteur, Université Paris Cité and the VRI have now provided part of the...
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Document de presse | 2023.10.25
The SARS-CoV-2 virus can migrate within neurons and infect the brain
The emergence of different variants of SARS-CoV-2 has produced a wide range of clinical profiles and symptoms in patients. For the first time, researchers at the Institut Pasteur and Université Paris Cité have demonstrated, in an animal model, a characteristic common to several SARS-CoV-2 variants: the ability to infect the central nervous system. The study confirms that SARS-CoV-2 is capable of...
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Portrait | 2024.01.15
Sarah Dellière: from hospital to lab, a scientist without borders
"Nothing in life is to be feared, it is only to be understood." These words from Marie Curie neatly sum up the philosophy and career of Sarah Dellière. She is determined, optimistic and adventurous, and she loves stepping out of her comfort zone to embrace new experiences and further deepen her knowledge.At the age of just 17, Sarah Dellière began traveling to far-flung corners of the world to...
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News | 2022.04.28
Understanding how the whooping cough bacterium has evolved in response to vaccination
In a recent study stemming from an international partnership involving several Institut Pasteur scientists, work was carried out on modeling the spatial dynamics and evolution of Bordetella pertussis, the bacterium responsible for whooping cough.
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News | 2022.07.08
Conversation: 2021, a pivotal year for the Institut Pasteur's future
Institut Pasteur Board of Governors Chairman Christian Vigouroux and President Prof. Sir Stewart Cole share their thoughts on the year's highlights. 2021 was a pivotal year poised between maintaining financial stability and supporting scientific projects.
