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News | 2024.05.15
The untapped potential of cycling for public health and the climate
A national study has revealed that cycling benefits health, the economy and the climate in France. The findings show that cycling can prevent nearly 2,000 deaths each year and that every kilometer cycled saves €1 in medical costs. The unprecedented study was conducted by researchers in the joint CNAM-Institut Pasteur PACRI unit, in collaboration with the CNRS.
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News | 2022.07.09
Conversation: capacity building to prepare for the future
Institut Pasteur Senior Executive Scientific Vice-President Christophe d'Enfert provides a brief, cross-disciplinary overview of 2021 covering capacity building, enhanced partnerships and future technologies.
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News | 2022.08.05
Our own RNA triggers an immune response to viral infections
An immune receptor normally known for identifying viral RNA is also capable of binding to cellular RNA to induce immune defenses. This mechanism could trigger immunity against viruses before they become detectable.
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News | 2024.09.18
Whooping cough: how do we explain its resurgence in 2024 in France?
In a study coordinated by the Institut Pasteur, scientists describe the dynamics of the whooping cough epidemic in 2024 in France, the worst in 25 years. The scientists also sequenced the genome of almost 70 bacterial isolates collected during the outbreak from January to mid-2024. These analyses allowed them to put forward several theories explaining the current resurgence in circulation of the...
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Document de presse | 2022.07.13
Light shed on SARS-CoV-2 replication in bat cells
Bats are reservoir species for numerous viruses including coronaviruses. Given that they do not appear to be affected by diseases transmitted by these viruses, there is potential benefit in understanding how their immune system regulates infection. Scientists at the Institut Pasteur and the CNRS studied SARS-CoV-2 replication in bat cells, which involved using real-time imaging techniques for the...
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News | 2022.11.14
Monkeypox: a detailed profile of the disease
Physicians and scientists from the Institut Pasteur, the Pasteur Network and ANRS | Emerging Infectious Diseases have conducted a review of the medical and scientific literature about monkeypox. The review, which paints a complete picture of the disease, was published in the New England Journal of Medicine on October 26, 2022. What are the signs of this disease? Where does it come from? How is it...
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Portrait | 2022.12.13
Pierre-Marie Lledo: a neuro-optimist in work and in life
Perception, emotions, behavior, decision-making, memory, good mental health, depression – these are some of the research topics that interest Pierre-Marie Lledo. With his team of biologists, physicians, mathematicians, biophysicists and biochemists, he is working to uncover some of the most intimate mechanisms in the brain.
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Document de presse | 2023.01.13
Using paleogenomics to elucidate 10,000 years of immune system evolution
Scientists from the Institut Pasteur, Université Paris Cité, the CNRS and the Collège de France have used paleogenomics to trace 10,000 years of human immune system evolution. They analyzed the genomes of more than 2,800 individuals who lived in Europe over the past ten millennia. They were able to date the increase in frequency of most of the mutations that are advantageous in defending against...
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Document de presse | 2023.10.25
New discovery concerning receptors used by coronaviruses to enter human cells
The SARS-CoV-2 virus responsible for COVID-19 can cause severe acute respiratory syndrome, contrasting with other coronaviruses that were known to cause mild seasonal colds prior to its emergence in 2019. This raises the question of why one coronavirus affects humans more severely than another. Scientists at the Institut Pasteur, Université Paris Cité and the VRI have now provided part of the...
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Document de presse | 2023.10.25
The SARS-CoV-2 virus can migrate within neurons and infect the brain
The emergence of different variants of SARS-CoV-2 has produced a wide range of clinical profiles and symptoms in patients. For the first time, researchers at the Institut Pasteur and Université Paris Cité have demonstrated, in an animal model, a characteristic common to several SARS-CoV-2 variants: the ability to infect the central nervous system. The study confirms that SARS-CoV-2 is capable of...
