Jacques Ravel, PhD, Professor of Microbiology and Immunology, as well as Associate Director for Genomics at the Institute for Genome Sciences (IGS), both at the University of Maryland School of Medicine, has been named a 2015-2017 Blaise Pascal International Research Chair, one of the most prestigious European science awards. He is spending this year working at the Institut Pasteur in Paris, and over the next two years will divide his time between Paris and Baltimore. He focuses on the human microbiome and its role in women’s health.

L'Institut Pasteur de Bangui a confirmé un foyer de virus monkeypox, à Bangassou à environ 800 km de Bangui la capitale de la République centrafricaine.

The Institut Pasteur in Bangui confirmed cases of monkeypox virus infection in Bangassou about 800 km from Bangui capital city of the Central African Republic.

A team from Doctors without Borders Belgium located in this area at the border of the Democratic Republic of the Congo, has collected samples from two children of the same family who presented with rashes (maculopapular) after consuming thryonomys meat a rodent locally known as sibissi.

Using innovative technology, scientists from the Institut Pasteur and Inserm have filmed in vivo the process by which an AIDS vaccine candidate, developed by the French Vaccine Research Institute and the ANRS, triggers the immune response. This previously unseen footage clearly shows how the vaccine recruits the immune cells needed to destroy infected cells. These results shed new light on the mode of action and potential of this vaccine.

Grâce à une technologie innovante, des chercheurs de l’Institut Pasteur et de l’Inserm sont parvenus à filmer in vivo le déclenchement de la réponse immunitaire par un candidat vaccin anti-sida développé par l’Institut de Recherche Vaccinale et l’ANRS. Ces images inédites montrent l’action précise du vaccin quant au recrutement des cellules immunitaires nécessaires à la destruction des cellules infectées. En permettant de mieux comprendre le mode d’action du vaccin, ces résultats valident son potentiel.

Le laboratoire de virologie de l’Institut Pasteur de la Guyane (Centre National de Référence pour les arbovirus, laboratoire associé pour les Antilles et la Guyane) vient de confirmer le 1er cas d’infection à virus Zika en Guyane. A ce jour, aucune transmission locale n’a été mise en évidence. Ce cas est importé du Surinam où le mois dernier, le laboratoire de virologie de l’Institut Pasteur de Guyane avait déjà confirmé le premier cas d’infection à virus Zika.

The virology laboratory of the Institut Pasteur in French Guiana (National Reference Centre for arboviruses, associated laboratory for the Antilles and French Guiana) has just confirmed the first case of Zika virus in Guiana. To date, no local transmission has been identified. This case was imported from the neighboring Surinam where the Institut Pasteur in French Guiana virology laboratory already confirmed last month the first case of Zika virus infection .

Plus d’un million de cellules meurent toutes les minutes dans un corps humain adulte. Que deviennent-elles ? Comment la mort cellulaire influence-t-elle l’ensemble des organes et des tissus vivants, notamment le système immunitaire ? Comprendre comment les différents types de mort cellulaire influence l’immunité est un sujet de recherche majeur pour le développement de thérapies s’appuyant sur une activation du système immunitaire.

Scientists have recently published a paper in which they reveal mayor players in the severe muscle damage caused by sepsis, or septicemia, which explains why many patients suffer debilitating muscle impairment long-term after recovery. They propose a therapeutic approach based on mesenchymal stem cell transplantation, which has produced encouraging results and has proved successful in restoring muscle capacity in animals.