Pathogen genomics and microbiota (8 entities)

Research in this thematic area explores the genomes of infectious agents in relation with their evolution. It also investigates the regulation of the microbiota composition and the mechanisms by which microbiota dysbiosis influences antimicrobial immunity.

Sylvain Brisse - Biodiversity and Epidemiology of Bacterial Pathogens

Klebsiella Pneumoniae (Urinary Tract, Respiratory and Blood Infections); Bordetella Pertussis (Whooping Cough); Corynebacterium Diphtheriae (Diphtheria); Strain Taxonomies; Antibiotic Resistance; Immune Response.

See the website of the unit

See the website of the French National Reference Center for Whooping Cough and other Bordetella infections

See the website of the French National Reference Center for Corynebacteria of the diphtheriae complex

See the website of the Bioinformatics developments for whole-genome sequencing of microbial agents for epidemiological surveillance project

Roland Brosch - Integrated Mycobacterial Pathogenomics

Mycobacterium Tuberculosis; Pathogenicity; Anti-tuberculosis Vaccine Development; New Anti-Tuberculosis Drugs Identification

See the website

Carmen Buchrieser - Biology of Intracellular Bacteria

Legionella; Genomics; Virulence Factors; Cell Biology of Infection

See the website

Christophe d’Enfert - Fungal Biology and Pathogenicity

Candida Albicans; Opportunistic Yeasts; Nosocomial Infections; Immunocompromized Individuals; Pathogenicity; Biofilm; Gastrointestinal Colonization; New Antifungal Drug Identification; Candida glabrata; Candida auris

See the website

Eugene Gladyshev - G5 Fungal Epigenomics

Neurospora crassa; DNA-DNA Interactions; DNA Homology Recognition; Repetitive DNA; Genetics

See the website

Philippe Glaser - Ecology and Evolution of Antibiotics Resistance

Enterobacteriaceae; Carbapenem Resistance; b-lactamase; Bacterial Fitness; Gut Microbiota

See the website

Simonetta Gribaldo - Evolutionary Biology of the Microbial Cell

Veillonella Parvula; Methanobrevibacter Smithii (anaerobes); Micro-organism Diversity and Evolution; Comparative Genomics, Phylogenomics; Gut Microbiota; Cell Envelope

See the website

Didier Mazel - Bacterial Genome Plasticity

Vibrio Cholerae; Gene Acquisition and Exchange in Bacteria; Horizontal Gene Transfer; Integron; Antibiotic Resistance

See the website