human genetics
News
2020.10.16
Hantaviruses are rodent-borne viruses causing serious zoonotic outbreaks worldwide for which no treatment is available. X-ray structures of the hantavirus...
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2020.07.09
Diagnosis of sleeping sickness, a neglected tropical disease caused by African trypanosomes, relies on the detection of parasites in blood. Following their...
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2020.02.08
In nature, female mosquitoes take successive blood meals during which they are exposed to a variety of microbes present in the host. In Africa, Trypanosoma...
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2020.08.04
Resistance to artemisinin, the main component of current antimalarial treatments recommended by WHO, is widespread in South-East Asia, but has not been...
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2020.10.17
Ludovic Deriano’s Unit studied cells mutated for NHEJ, the canonical repair pathway for DNA double-strand break. The researchers showed that those transformed...
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2021.05.03
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Emerging and re-emerging viruses are key players among the different pathogens that have caused recent epidemics, as attested by several...
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2020.03.05
Cells in vivo organize into 3D structures that underlie the shape and mechanics of tissues, as well as their biological function. Researchers mapped how...
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2020.07.16
Triplet repeat expansions are responsible for more than two dozen neurological and developmental disorders. Shortening these repeats with endonucleases could...
News
2020.03.27
Replicative DNA polymerases have evolved the ability to copy the genome with high processivity and fidelity. In Eukarya and Archaea, their processivity is...
News
2021.04.30
It remains unclear whether and how neural stem cells (NSCs) are maintained at long-term in the vertebrate brain. Combining intravital imaging, genetic tracing...