Research

The Institut Pasteur is an internationally renowned center for biomedical research that stands out in many disciplines. By deciphering the fundamental mechanisms of living organisms, its researchers contribute to the advancement of knowledge that leads to cutting-edge medical applications, ultimately improving public health.

Research at the Institut Pasteur is based on four key strengths:

  • research conducted at all levels of life, from molecules to individuals and populations;
  • multidisciplinary strategies, focusing on molecular and cellular approaches as well as bioinformatics, biophysics, chemistry and nanotechnologies;
  • unique technological facilities, including the most powerful microscope in the world (Titan);
  • an international network of 32 institutes, (the only one of its kind in the world), which is present on every continent.

Combining these resources is essential to responding to the major public health challenges of today, for example antibiotic resistance, the impact of microbiota (formerly called gut flora) on our health, promoting healthy aging, etc. Institut Pasteur is engaged on these fronts and its discoveries improve prevention, diagnosis and treatment of infectious diseases (Ebola, malaria, AIDS, tuberculosis, Zika, etc.), neurodegenerative diseases (Alzheimer's, Parkinson's, etc.), cancers (uterine, stomach, etc.), autism, etc.

Thanks to strong interdisciplinary and international capacities, at the Institut Pasteur, diverse research fields and expertise synergize to generate major breakthroughs in biomedicine. In this way, an understanding of the fundamental mechanisms of cell motility benefits cancer researchers studying metastasis dissemination. Similarly, characterization of the genetic and environmental factors that influence our immune response, whether through infection or vaccination, paves the way for personalized medicine. 

These examples show the vital role of Institut Pasteur’s fundamental research and its impact on clinical research to the benefit of patients. This positive influence on public health is also seen in Institut Pasteur’s educational mission, a commitment to share knowledge with future generations of researchers and doctors.  

Christophe d'Enfert - Institut Pasteur
 

Christophe D’Enfert,
Scientific Director
of the Institut Pasteur

Contributing to the development of novel diagnostic, preventive and therapeutic approaches to diseases has been fundamental to the Institut Pasteur's missions since its inception more than 130 years ago. Emerging infectious diseases, antimicrobial resistance, neurodegenerative and behavioral diseases, and cancer research have been placed at the heart of our development strategy for the coming years. Finding solutions to these health issues requires cutting-edge basic research, but also a commitment to translating our discoveries into innovations for patients, in conjunction with hospitals and industry. At the Institut Pasteur, we provide a favorable technological environment to enable our teams of talented researchers to contribute as fully as possible to tomorrow’s fundamental discoveries and biomedical innovations.

 

 

Departments

Département de Biologie cellulaire et infection - Institut Pasteur

Cell Biology and Infection

Shedding light on the intricate workings of microbes and cells is the focus of research conducted in this department.

Computational Biology

We live at a time when biology is producing vast reams of data, which can only be deciphered using mathematical modeling

Département de Biologie du développement et cellules souches - Institut Pasteur

Developmental and Stem Cell Biology

How do cells acquire their identity? How are organs formed? Little is known about the mechanisms behind the “development” of animals, including human beings.

Département Génomes et génétique - Institut Pasteur

Genomes and Genetics

Exploring the genomes of bacteria, yeast, insect vectors and ultimately humans.

Département Infections et épidémiologie - Institut Pasteur

Global Health

The main objectives of the interdisciplinary Department of Global Health are to study infectious diseases and tackle the emergence of new pathogens.

Département d'immunologie - Institut Pasteur

Immunology

The complexity of the immune system is a never-ending source of fascination for scientists.

Département de Microbiologie - Institut Pasteur

Microbiology

Bacteria have always been important research models at the Institut Pasteur.

Département de Mycologie - Institut Pasteur

Mycology

Mycoses have been a major public health issue since the early 1980s.

Département de Neurosciences - Institut Pasteur

Neuroscience

The nervous system has yet to reveal all its secrets.

Département Parasites et insectes vecteurs - Institut Pasteur

Parasites and Insect Vectors

Parasitic diseases are all too often neglected. However, they affect close to 3 billion people in the world.

Département de Biologie structurale et chimie - Institut Pasteur

Structural Biology and Chemistry

Observing life at atomic level because chemistry is the motor of life.

Département de Virologie - Institut Pasteur

Virology

Fighting viral infections that affect human health.

 

Centers of the Institut Pasteur

Center for Translational Science

Facilitating new biomedical projects and contributing to the advancement of medicine – these are the missions of the Center for Translational Science, set up in 2014.

Center for Technological Resources and Research

The Center for Technological Resources and Research (C2RT) is home to four Technology and Service Units (UTechS) and 12 Technological Platforms.

Center for Animal Resources and Research

At Institut Pasteur, we provide our research groups with the necessary infrastructure to use animal models in the best ethical and regulatory conditions.

Hearing Institute

A center for fundamental and medical research into hearing, created by the Fondation Pour l'Audition and the Institut Pasteur.

 

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